Minimal VA loss, leakage associated with ‘early’ neovascular AMD | Ophthalmology


WAILEA, Hawaii – Early choroidal neovascularization should be identified when small and extrafoveal, and should be associated with minimum visual acuity loss and other characteristics not previously thought of in early detection,


“Many people’s concept of early is what we would call late,” Bressler said. For example, visual acuity loss of 20/80 or 20/100 would be a late indicator of


“We want to get these cases when [visual acuity] is 20/40 or better,” Bressler said, because the goal is minimal visual acuity loss from baseline.


The pattern on fluorescein angiography ideally should be occult, he said, before it becomes the classic pattern that presumably represents neovascularization that has proliferated beyond the


“We want to get these [cases] when the baseline visual acuity and lesion size are relatively small because that predicts who is going to do the best,” Bressler said. “I hope we will change our way of detecting these. As we have with early macular holes, as we have with early diabetic macular edema, we need to do the same with


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